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Additionally, ketamine activates the NLRP3 inflammasome, inducing caspase-1 activation and neuronal pyroptosis, further contributing to neuroinflammation in regions, such as the hippocampus and prefrontal cortex (Zhang et al., 2021)

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It has been reported that FDG brain hypometabolism in the pre-frontal cortex is also present in multiple neurodegenerative disorders (such as Parkinsons disease and AD) (24, 112, 113) and neuropsychiatric conditions (114)

For the best results, use twice a day NOTE: Food supplements should not be used as a substitute for a balanced diet and a healthy lifestyle

For fitness enthusiasts, it is often most effective when taken 30 to 60 minutes before exercise or with a primary meal to optimize absorption