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The results indicate that glyphosate exposure caused significant genotoxic and physiological disturbances in V

5a) led to a decrease in the expression of GPX4 in a time- and concentration-dependent manner, and a cumulative effect was observed when using fluvastatin and RSL3, showing that both contribute to ferroptosis

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These lesions were largely absent or attenuated in GHRP-6-treated animals

Since GPX4 plays a crucial role in the clearance of lipid peroxidation by utilizing GSH as its substrate, serving as the primary inhibitor of cellular ferroptosis 41,42 , we examined the impact of TB m A-Glu on the expression level of GPX4 in HepG2 cells