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Analysis of comprehensive molecular, genetic, and phenotypic data should provide unprecedented understanding of breast cancer biology and enable more precise, personalized interventions

The same is true for another myeloproliferative disorder: in blast crisis of chronic myeloid leukemia we have found the correlation of the expression of functionally active Pgp and the expression of the antigens of early myeloid differentiation--CD34 and CD13 [33]

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Alternatively, the increased QUIN/KYN ratio in PTSD could also derive from a different distribution of KYN in body compartments, such as increased passage of this molecule through the BBB or its recruitment for binding to the aryl hydrocarbon receptor (Ahr) that promotes ROS modulation, all of which could potentially occur during the induction of cytokine release and inflammation present in these patients (142)