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In addition, supply of SAM restored ferroptosis markers, which was wiped off by methylation inhibitor ADOX (Fig

These authors showed that the synbiotic based on Lactobacillus salivarius was involved in the activation of pathways related to fat and carbohydrate metabolism, cell adhesion, and immune response, while the synbiotic based on Lactobacillus plantarum was involved in the upregulation of expression of genes involved in metabolic pathways (154)

However, this experiment was conducted in cultured neurons and, in a physiological context, the CB 1 receptor is not easily able to enhance glutamate release because the inhibition of cAMP also suppresses the key active zone proteins, like Munc-13 and RIM, necessary for vesicle docking

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