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In terms of the gap in life expectancy between the United States and other countries in 2003, Preston and colleagues find that differences in the estimated damage caused by smoking account for 78 percent of the 1.6-year gap for women and 41 percent of the 0.8-year gap for men

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We then evaluated whether the decreased electrical resistance coincided with an increase in the small molecule permeability of the epithelial barrier

It all began when Hoogendoorn, a smoker himself who tried to quit for at least 20 years, puffed on an electronic cigarette and decided that he could do better

Figure 2 provides an overview for how this process may unfold in a primary care setting, including addressing situations where patients are ambivalent about quitting smoking