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While the IOM had based B12 needs on the amount required to correct hematological parameters for people with pernicious anemia, the EFSA had almost 20 more years of research to draw on, and concluded that the most suitable approach was basing needs on biomarkers (serum B12, holotranscobalamin, MMA, and homocysteine)

...for every ton of CRT display products manufactured, 2.9 metric tons of carbon were released is a piece from Rebecca Admas in which they are also highlighting the emission released in the manufacturing process