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In sum, as summarized in Figure 8, our data indicate that, in smoking-induced COPD/emphysema, miR-125a-5p via Sp1 regulation of SIRT1/HIF-1 is involved in the senescence of lung epithelial cells

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A situation can become associated to panic if someone has had a previous reaction before in similar contexts, but more often panic is triggered by fear of entrapment in a potentially phobic environment such as a plane

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In the months following her passing, and to celebrate what would have been her 57th birthday, we caught up with bandmates, friends, and admirers to whom Sinad OConnor inspired creatively and personally, and in many cases, changed their lives