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Smoking Prevalence Around the World Worldwide, approximately 23% of adults, including more than 1 billion males and 250 million females, smoke tobacco products

The data showed no inflammatory response or emphysematous changes in the lungs from mice exposed to e-cigarette vapor (e-vapor) compared to CS exposed mice, but there were significant alterations in the lipid profiles of both alveolar type II cells and alveolar macrophages (AM) after e-vapor exposure [53]

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The polarized nature of the respiratory epithelial barrier results in the segregation of receptors and other factors between their apical and basolateral surfaces, which is important in maintaining tissue homeostasis

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