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Environmental factors such as exposure to pesticides 6,7 or history of melanoma 8 have been associated with increased PD risk, whereas alcohol intake 9,10,11 , smoking 12,13,14 , caffeine consumption 15,16 , and educational attainment 17 are associated with reduced risk 1,18

Metabolism of Nicotine The liver is an essential organ for detoxification, playing a significant role in metabolizing nicotine, the addictive substance in cigarettes

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