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[7] E-cigarettes were illegal in Japan, which forced the market to use heat-not-burn tobacco products for cigarette alternatives

Prescription medications to help you quit smoking, such as varenicline (Chantix) and bupropion (Zyban), may also be effective for quitting smokeless tobacco

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But if they cannot quit smoking combustible cigarettes, they should consider using novel nicotine products to either quit smoking altogether or to reduce their harm by transitioning fully to these products. Going forward, work needs to be done to better understand the non-cancer risks associated with e-cigarettes, such as respiratory and cardiovascular disease