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Breaching the blood-brain barrier is a serious matter: It means the brain's environment, which needs to be extremely stable for nerve cells to function properly, can be perturbed in all kinds of dangerous ways

A woman falls down and gets dog feces on her coat (we see a stain on her coat during the rest of the movie)

Nicotine addiction can be difficult to overcome and has various health and social consequences

Generalization of conditioned fear-potentiated startle in humans: Experimental validation and clinical relevance

"You know my mother?" asks Roberto

As of 2017, Marlboro had 40% market share in the United States, more than the next 7 competing brands combined