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Nicotine contributes to this risk through: Vasoconstriction that weakens blood clot formation Mouth movements when inserting/adjusting pouches can dislodge clots Chemical irritation of the wound area Increased saliva production that can wash away protective clots ZYN pouches, while tobacco-free, still contain nicotine salt and food-grade fillers that can irritate surgical wounds or introduce bacteria to the extraction site during the critical 72-hour initial healing phase

*EDITORS NOTE : Researchers used established methods to identify youth who are at risk of future cigarette smoking

The resulting red, swollen gums called gingivitis can lead to irreversible bone loss

Synthetic nicotine e-cigarette vending machines will be restricted to designated locations and required to have adult verification systems

"It's impossible to know what the dosage is since these guys are making this stuff themselves," Glantz tells The Salt