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A German doctor, Samuel Hahnemann, invented it in the 18th century

Scientists have been concerned about this question because cannabis and tobacco smoke have some of the same contents shown to have toxic effects on the lungs

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Furthermore, NNALa metabolite formed after 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) enters the body and a well known carcinogenurinary levels increased markedly after hookah use, indicating the presence of tobacco-specific nitrosamines in hookah smoke [63, 82]