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Mechanism of Action The bactericidal action of ciprofloxacin results from inhibition of the enzymes topoisomerase II (DNA gyrase) and topoisomerase IV (both Type II topoisomerases), which are required for bacterial DNA replication, transcription, repair, and recombination

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While the store is operated by a group posing as shadow members of the Cayuga Nation, it is not affiliated with the Cayuga Nation, has not been approved by the Cayuga Nation Council, and it is not covered under the Nations sovereign immunity. Halftown said the town has tacitly blessed the selling of cigarettes at residentially zoned locations and the Cayuga Nation is pleased to follow their lead and sell our Cayuga brand of cigarettes at locations on our reservation. Halftown and his supporters claim the reservation established by the 1795 Treaty of Canandaigua, covering more than 60,000 acres, has not been disestablished by Congress since that agreement