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Second, smoking-associated or methylation-associated confounding factors, such as alcohol consumption and body mass index, which were not adjusted for in many of the studies we included, may contribute to the heterogeneity

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Discoloration - Chewing tobacco is a habit that can cause discoloration of the teeth

Jaghbir M, Shreif S, Ahram M

Tobacco Companies say they dont market to kids and even claim they want people to quit smoking