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If syphilis is left untreated during pregnancy it can lead to early birth, low birth-weight, stillbirth, death shortly after birth or other sequelae in the baby, including inflammatory manifestations affecting the eyes, ears and joints, as well as skeletal malformations resulting from developmental damage during the early stages of syphilis

The relative importance of the LOF, DNE and GOF effects of mutant p53 in the initiation, sustained growth and metastasis of cancer is still hotly debated, as is how the different p53 mutations affect these tumorigenic processes

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Durk was enraged by this response the more so when he learned that the tobacco companies already employed an under-the-wrapper stamp for a number of foreign countries, including some very small ones, like Yemen

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