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CONCLUSIONS This study suggests that initiating cigarette smoking early during adolescence is associated with reductions in HRQOL in later adulthood

Lighting up: Can smoking cause seizures

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There was no statistically significant difference in age and BMI

Modifies rule of evidence to establish an evidentiary presumption that nicotine is addictive and certain diseases are caused by tobacco use

For example, although EGFR mutations are more common in never-smokers, one-third of lung cancers with EGFR mutations occur in smokers therefore, knowledge of driver mutations and corresponding treatments gleaned from studies of never-smokers may benefit smokers with the disease