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(Cancer medications or those that reduce stomach acid.) Vitamin B12 deficiency can also occur in children, often from birth, and may present as a developmental delay or even autism

Side effects from B12 supplementation are uncommon but may include: Mild gastrointestinal symptoms such as nausea or diarrhoea, typically with very high oral doses Headache or dizziness in some individuals Skin reactions (rash, itching) at injection sites when using intramuscular preparations Rare but serious allergic reactions, including anaphylaxis with injectable forms Hypokalaemia (low potassium) may occur during rapid correction of severe megaloblastic anaemia If you experience symptoms of a severe allergic reaction (difficulty breathing, severe rash, swelling of face or throat) after taking B12, seek immediate medical attention

Retrieved from Pawlak, R., Lester, S

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They combined this targeting sequence with a proapoptotic domain, D(KLAKLAK)2, that disrupts mitochondrial membranes when internalized by cells