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10.1126/scitranslmed.3003062 [DOI] [PMC free article] [PubMed] [Google Scholar] Lewis JC, Sutter ME, Albertson TE, Owen KP, Ford JB, 2014

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If the graphic warnings were put in place this year, the number of deaths due to smoking-related heart disease, lung cancer and chronic obstructive pulmonary disease would drop by an estimated 652,800 over 50 years, the researchers predicted

Nicotine cravings, irritability, and mood swings are common

Early symptoms of tobacco use include coughing, bad breath, yellow stains on the fingers and teeth, and impaired sports performance

Regardless, Brand X is a decent little Monster of the Week, a clever mystery wrapped around some gross set pieces and a solid villain