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It is injected subcutaneously, usually into the abdomen or thigh, and the dose may be adjusted based on your treatment plan

Mechanistically, TXNIP antagonizes Trx1 by forming a disulfide bond with its Cys32 residue, leading to Trx1 inactivation and increased ROS levels, thereby facilitating lipid peroxidation and ferroptotic signaling

Imtaiyaz Hassan, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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Brain Corticosteroid Receptor Balance in Health and Disease