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Why flavored vape products may be attractive: Green apple tobacco flavor elicits reward related behavior, upregulates nAChRs on VTA dopamine neurons, and alters midbrain dopamine and GABA neuron function ScienceDirect Nicotine extends duration of pleasant effects of dopamine Mechanism based medication development for the treatment of nicotine dependence Acta Pharmacologica Sinica Chronic nicotine increases midbrain dopamine neuron activity and biases individual strategies towards reduced exploration in mice Nature Communications Are Smokers Addicted To Dopamine? Smokefree Where to start with stopping smoking
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