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In 1688 John Clayton wrote, "I have observed, that that which is called Pine-wood Land tho' it be a sandy soil, even the sweet-scented Tobacco that grows thereon, is large and porous, agreeable to Aranoko Tobacco

Studies suggest that other chemicals in tobacco smoke, such as acetaldehyde, may enhance nicotines effects on the brain

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Harm reduction refers to the concept that it is more practical to reduce the harm associated with using certain products rather than attempting to eliminate that harm completely through counterproductive policies like ineffective bans or punitive levels of taxation

This product contains nicotine, which is a highly addictive substance.

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