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showed higher concentrations of circulating markers of endothelial function in smokers including sICAM-1, sE-selectin, and sP-selectin, but lower concentrations of sL-selectin and sVCAM-1 compared to never-smokers [18]

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In addition, cigarettes have entered every aspect of American culture from films and advertising to fashion and music

A Report of the Surgeon General: Preventing Tobacco Use among Youth and Young Adults

Among respondents, 289% were never smokers or non-smokers, 269% were former smokers, 255% were daily smokers, and 189% were occasional smokers (see Supplementary File 6 for the smoker status of the respondents)