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Although several of these studies have reported Nrf2 pathway as being central to the anti-inflammatory and antioxidant effects of the aforementioned lipid mediators and polyunsaturated fatty acids, the precise molecular mechanism involved in the activation of Nrf2 was not demonstrated

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CORTISONE INJECTIONS ARE USUALLY ONLY RECOMMENDED AS A SHORT-TERM TREATMENT While they can be very effective, too many injections of cortisone over a short period of time have been shown to cause damage to the tendons, ligaments, and cartilage at the injection site

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