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The answer, the memo author argued, was obvious: In this situation, business theory strongly suggests that we should learn as much as possible about this threat to our present product. How much of a threat marijuana truly presented to a highly addictive product already used by nearly 40 percent of American adults is unclear, but cigarette-makers took notice

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29 At temperatures up to 250 C, in the presence of the sugar alcohol glycerol (common in tobacco/nicotine products including e-cigarettes), sucralose generates several chloropropanols including the carcinogen 3-monochloropropanediol