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At clinical concentrations, pretomanid does not inhibit major CYP isoenzymes, including CYP1A2, CYP2C8, CYP2C9, CYP2C19 or CYP2D6, and does not induce CYP2C9 or CYP3A4, limiting the potential for DDI trough CYPs

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To assess the robustness of our findings and minimize the impact of confounding variables, including smoking, snus or cannabis use, excessive alcohol consumption, recent antibiotic use, and chronic somatic diseases, the study design included a sensitivity analysis where these participants were excluded (Fig

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If your practice consistently bills for high-complexity visits for a standard case of ICD 10 bronchitis, your "cost" score could suffer, leading to negative payment adjustments

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