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These differences complicate the ability to assess smoking-induced microbiome alterations and associated disease mechanisms in humans [140, 141]

As another example, because the prevalence of smoking varies by as much as threefold among the states, the voters in a state with more smokers may find public smoking regulations more oppressive than the voters in another state with fewer smokers

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Its all behind closed doors, said Judith Mackay, a special adviser to the Global Center for Good Governance in Tobacco Control with years of experience dealing with the tobacco industry in Asia

Thats over 500,000 deaths more annually, than WHOs most recent estimate of 8.1 million deaths a year from smoking