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The National Cancer Institute states that cigarette smoking is the leading preventable cause of disease and death in the United States, as smoking causes cancers of all the following: lung, esophagus, larynx (voice box), mouth, throat, kidney, bladder, liver, pancreas, stomach, cervix, colon and rectum, as well as acute myeloid leukemia

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Smoking, however, has also been linked to mental health problems, such as two to three times higher rates of clinical depression in smokers than in non-smokers, according to a study published in the journal PLOS ONE