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Interestingly, they found that animals exposed to nicotine prenatally and given nicotine during adolescence had worse outcomes and greater neurotoxicity as compared to controls, indicating the neurotoxicant actions may contribute towards the association between PNE and subsequent smoking in offspring

It does so by combining measures for reducing smoking prevalence, especially those that deter initiation and encourage stopping, with measures that reduce exposure to toxicants in smokers who would otherwise continue smoking

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Most people try to cut down by willpower alone, and that usually backfires