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[2] An important caveat applies to all of this work: these studies measure DSIP-like immunoreactivity (DSIP-LI) using antisera, which detects material that cross-reacts with the antibody

Prospective trials incorporating longitudinal monitoring of neurological parameters and biomarker profiling are critically needed to validate these pharmacovigilance signals while elucidating doseresponse relationships and underlying mechanisms

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A one-time dose of Beqvez reduced bleeds post-treatment compared to standard of care with a median of zero bleeds after up to three years of follow-up, Pfizer reported, adding that this could potentially help patients avoid years of treatment burden