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4 Interest in quitting tobacco has grown in the US, and societal patterns of its use are changing as more people smoke fewer cigarettes but continue to use nicotine through other avenues, such as e-cigarettes or hookah smoking

Regulations, such as the European Unions Tobacco Products Directive (TPD) , which caps nicotine content at 20mg/ml , mandate manufacturers to adhere to these standards

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Finally, adjusted binary logistic regression was used to assess the association between e-cigarettes and other tobacco forms