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Unfortunately, the desirable aromas and flavors are part of a large mixture of chemicals formed upon combustion, so with the antimicrobial chemicals also come, most unfortunately, irritants and carcinogens

PLoS ONE 16 , e0246321 (2021)

North Carolina and South Carolina come in third and fourth at $5.32 and $5.47 per pack, respectively

Mutat Res (2012) 736:6474.10.1016/j.mrfmmm.2011.06.004 23 StepanovIKnezevichAZhangLWatsonCHatsukamiDKHechtSS

According to the NHS, smoking is the primary cause of preventable illness and premature death, accounting for approximately 74,600 deaths a year in England