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Consistent with the trend of decreased cysteine levels, neuroprotective intermediates in the downstream taurine/hypotaurine metabolism pathway also exhibited a trend toward depletion (Levin et al., 2014) (Figure 3E, metabolite determination results are shown in Supplementary Tables S10)

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Targeting ferroptosis in Parkinson's disease: mechanisms and emerging therapeutic strategies

Franco C, Paz-Filho G, Gomes P, Nascimento V, Kulak C, Boguszewski C, et al

A.MagdyM.IsmailA.AttiaA.AhmedH.et al

However, evidence is lacking about whether this is also true for human cases of ALS