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This intrinsic vulnerability is compounded by a weak copper export system, characterized by low expression of ATP7A/B transporters, which facilitates toxic accumulation [100]

The subcutaneous injection routes common in community use have not undergone formal safety evaluation

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However, the successful identification of the small intestine-specific NMN transporter Slc12a8 has partly answered this question [77]

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810nm near-infrared light offers neuroprotection and improves locomotor activity in MPTP-treated mice