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Toxicology 365, 4858

Consequently, motor symptoms, including bradykinesia and tremors, occur (83, 84)

Butyrate is a primary energy source for colon epithelial cells and a potent histone deacetylase (HDAC) inhibitor (199).Through this epigenetic mechanism, it promotes Treg cell differentiation while suppressing pro-inflammatory responses, ultimately maintaining intestinal immune tolerance (146)