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In the previous pilot clinical trial, an effect on survival was observed using a dosage of 3 g/day, while in our observational study, the effective dose was 1.5 g/day and, unexpectedly, no effect was observed in subjects treated with 3 g/day

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Vitamin B12 is essential for several critical processes in the body, including producing red blood cells, DNA synthesis, and keeping the heart and nervous system healthy

Female or male age-matched mice (712 weeks old) were used for all experiments (unless otherwise stated) and euthanasia was performed by cervical dislocation

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