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The review also highlights the relevance of the MM environment, focusing on the importance of the bone marrow (BM) niche

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166 These findings challenge the former hypothesis that high urinary urea concentrations caused by a high-protein diet might serve as a potential carcinogenic factor in the bladder, suggesting the urgent need for further investigation

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So, pancreatitis, pancreatic inflammation, or what we'd call exocrine pancreatic insufficiency, where the digestive processes of the pancreas are not being fulfilled normally