Mal-Lys(m-PEG4)-Val-Cit-PAB(m-PEG4)-Exatecan Size:5mg Sulforhodamine 101 emits at a

Sulforhodamine 101 emits at a longer wavelength than does either Tetramethylrhodamine or Sulforhodamine B

Azidoacyl-CA CAS Number Related CAS Molecular Formula C12H23ClN4O3 Molecular Weight 306

Product Name Mal-Propionyl-Beta-Ala-Val-Cit-PAB(m-PEG8)-MMAE Synonyms CAS Number Related CAS Molecular Formula C86H139N13O25 Molecular Weight 1755

4 SMILES OC(=O)CCOCCNC(=O)COC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

17515–17523

Mal-Lys(m-PEG4)-Val-Cit-PAB(m-PEG4)-Exatecan Size:5mg Sulforhodamine 101 emits at aSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by