Azide-Hexanoyl-Val-Cit-PAB(m-PEG8)-MMAE Size:1mg Product Name tert-butyl N-[4-(piperazin-1-yl)butyl]carbamate Synonyms

Product Name tert-butyl N-[4-(piperazin-1-yl)butyl]carbamate Synonyms 1-(4-Boc-aminobutyl)piperazine CAS Number 874831-61-5 Related CAS Molecular Formula C13H27N3O2 Molecular Weight 257

1038/nature18621

Product Name DCAF1 Binder 13 Synonyms CAS Number n/a Related CAS Molecular Formula C28H35ClN6O Molecular Weight 507

46 SMILES O=C(CCN1C(=O)C=CC1=O)NCCC(=O)N1CC2=CC=CC=C2C#CC2=CC=CC=C12 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

031 SMILES CC(C)(C)OC(=O)CN1CCN(CC(=O)NCCCCCNC(=O)CCN2C(=O)C=CC2=O)CCN(CC(=O)OC(C)(C)C)CCN(CC(=O)OC(C)(C)C)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Azide-Hexanoyl-Val-Cit-PAB(m-PEG8)-MMAE Size:1mg Product Name tert-butyl N-[4-(piperazin-1-yl)butyl]carbamate SynonymsSOLU KNEX cleavable linker features a Val Cit dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing