Mal-Lys(m-PEG4)-Val-Cit-PAB(m-PEG4)-MMAE AHPC S)-AHPC-CO-C10-NH2 HCl Synonyms CAS Number

S)-AHPC-CO-C10-NH2 HCl Synonyms CAS Number 2341796-75-4 Related CAS 2341796-74-3 (free base) Molecular Formula C33H53Cl2N5O4S Molecular Weight 686

369 SMILES BrCCOCCOCCOCCCC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

S)-AHPC-CO-C10-acid Synonyms CAS Number 2357115-09-2 Related CAS Molecular Formula C34H50N4O6S Molecular Weight 642

84 SMILES CC(C)(C)OC(=O)CN1CCN(CC(=O)NCCCO)CCN(CC(=O)OC(C)(C)C)CCN(CC(=O)OC(C)(C)C)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Compared to the original Cy5 dye

Mal-Lys(m-PEG4)-Val-Cit-PAB(m-PEG4)-MMAE AHPC S)-AHPC-CO-C10-NH2 HCl Synonyms CAS NumberSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to