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Sore-arm profiles All three FDA-approved COVID-19 vaccines are delivered via a needle into the arm, and all cause the same kind of poking pain that comes with a quick stab

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72 Cyanocobalamin (but not hydroxocobalamin) is also contraindicated in renal insufficiency

When delivered intranasally, its absorbed through the nasal mucosa into the bloodstream, allowing for quicker access to the brain and the central nervous system

Maren TH, Broder LEJ

[15] [16] Standard NHS treatment protocols: Without neurological involvement: Hydroxocobalamin 1mg intramuscularly three times weekly for two weeks, then maintenance injections every 2-3 months (lifelong if pernicious anaemia)