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Inappropriate antibiotic use across sectors, including clinical and animal health, has further escalated the global antibiotic resistance crisis, contributing to the emergence of MDR pathogens that resist multiple antibiotic classes (Yang et al., 2024)

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Therefore, the aim of this study was twofold: 1) to assess vitamin B12 serum levels in ME/CFS patients before and after use of high dose vitamin B12 nasal drops and 2) to compare the changes in function before and after starting therapy, using an activity meter, the physical functioning score of the Rand 36 questionnaire, and both the fatigue and concentration scales of CIS20r questionnaire

doi:10.1016/j.jhsa.2010.07.018 6

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