DBCO-Lys(m-PEG4)-Val-Cit-PAB(m-PEG4)-Exatecan Size:10mg Product Name DOTA-tris(t-Bu)ester-C6-azide Synonyms CAS

Product Name DOTA-tris(t-Bu)ester-C6-azide Synonyms CAS Number n/a Related CAS Molecular Formula C34H64N8O7 Molecular Weight 696

Product Name Phthalimidinoglutarimide-5'-propargyl-amine HCl Synonyms CAS Number n/a Related CAS Molecular Formula C16H16ClN3O3 Molecular Weight 333

491 SMILES [N-]=[N+]=NCCOCCOCCOCCNC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

328 SMILES OCCCNC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

284 SMILES OC(=O)CNC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

DBCO-Lys(m-PEG4)-Val-Cit-PAB(m-PEG4)-Exatecan Size:10mg Product Name DOTA-tris(t-Bu)ester-C6-azide Synonyms CASSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a DBCO Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further