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After scratching the cells to make a wound, 3 10 9 particles of fluorescently labeled l-EVs were added to the 4 10 6 cells in 200 l of phenol red-free DMEM medium (Gibco, #21063029) containing 10% EV-depleted FBS, and the cells were incubated for 1 h before the observation

Nature 555 , 5460 (2018)

With more time and study, its likely to be included in more treatments down the line

Examples include CD95 (Fas) and TNF-related apoptosis-inducing ligand (TRAIL)-receptor (TRAIL-R) that are activated by their ligands, Fas ligand (FasL) and TRAIL, present on NK cell membranes or secreted by NK-derived exosomes