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Clinically, this points to a bi-directional interaction between gut inflammation and brain inflammation, with mast cells acting as key transducers in both arenas 24

This bidirectional effect highlights the necessity for context-specific modulation of the autophagy-ferroptosis axis

HP 13 C MR via dissolution dynamic nuclear polarization (dDNP) is an emerging imaging technology that allows direct visualization of metabolic conversion of 13 C-enriched molecules, and has been applied extensively to study metabolism in cells, tissues, animal models, and patients 22,23,24

This enzymatic interaction underlies many of the peptides regenerative research applications

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Molecular determinants and genetic modifiers of aggregation and toxicity for the ALS disease protein FUS/TLS