Mal-Propionyl-Beta-Ala-Val-Cit-PAB(m-PEG8)-PNP Thalidomide Visualizing inflammation with an M1

Visualizing inflammation with an M1 macrophage selective probe via GLUT1 as the gating target

Product Name Lenalidomide-5'-CO-PEG4-C2-amine HCl Synonyms CAS Number n/a Related CAS 2727154-04-1 (free base) Molecular Formula C24H35ClN4O8 Molecular Weight 543

Among a series of related probes (PC1–9)

Azide has been extensively used in click chemistry

34 SMILES Cl

Mal-Propionyl-Beta-Ala-Val-Cit-PAB(m-PEG8)-PNP Thalidomide Visualizing inflammation with an M1SOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The PNP (para nitrophenyl) moiety serves as an activating leaving group, enabling efficient and selective conjugation of the payload to the linker. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as