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Interestingly, this effect was prevented by the administration of gadolinium chloride, which is an inhibitor of liver-residing macrophages known as Kupffer cells (68)

In old rats and mice compared to young, arginase activity was significantly increased and accompanied by decreased NO production and increased O 2 generation indicating eNOS uncoupling [129, 130]

86 LucarelliS.FredianiT.ZingoniA

These qualities make them particularly appealing for those who are new to peptide research or prefer time-saving solutions in their daily clinical study regime