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Studies on the children of strict vegans and vegetarians, who often have a latent vitamin B12 deficiency, showed severe developmental disorders (3-9)

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The methionine cycle metabolites are further reduced compounding the effects of trisomy 21

Symptoms of vitamin B12 deficiency can vary widely and may include fatigue, weakness, pale skin, shortness of breath, neurological symptoms such as numbness or tingling in the hands and feet, difficulty walking, memory loss, and mood changes