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In: Conns Current Therapy 2019

Mainly the NCOA4-, NADPH oxidase 4 (NOX4)-, activating transcription factor 3 (ATF3)-and p53-mediated mechanisms are crucial in modulating iron metabolism, lipid peroxidation and antioxidant defenses, thereby affecting the vulnerability to ferroptosis under physiological and pathological conditions (Fig

Exercise-induced skeletal muscle remodeling and metabolic adaptation: redox signaling and role of autophagy

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In eukaryotic cells, AMPK functions as a critical regulator of autophagy, orchestrating cellular energy balance and systemic energy metabolism (60)