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In addition to melatonin-related mechanisms, there is growing interest in uncovering the role played by circadian clock genes (such as CLOCK, BMAL1, PER1/2/3, CRY1/2, and NPAS2), which not only govern circadian timing but also regulate processes central to tumorigenesis, including cell cycle control, DNA damage response, metabolism, and immune regulation 25

Boron-doped CQDs (B-CQDs), namely Formulation 1 (F1) and Formulation 2 (F2), preserved greater than 86% viability across multiple cell lines, demonstrating organ-specific targeting capabilities relevant to bioimaging and drug delivery strategies [159]

Some may notice visible changes within just a couple of weeks, while others require longer treatment periods to achieve their post treatment goals

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